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“She refused a mastectomy in 2008 because her sister had died despite surgery and chemotherapy”

A patient presents with a history of metastatic breast cancer since 2009. Estrogen receptor-positive/HER2-Negative. She underwent most known chemo and hormone therapy. Is there any role for palliative surgery or cryotherapy?

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A synchronous diagnosis of two malignancies

“A 63-year-old male and recent immigrant from Nigeria presents with progressively worsening of shortness of breath and acute progression of a chronic right breast mass. An invasive breast carcinoma was diagnosed by the core biopsy of the right breast mass. Within two months of his breast cancer diagnosis, the patient also was diagnosed with…”

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These cases were originally published in the most recent edition of The Differential for Cancer newsletter. The Differential is our premium newsletter which rounds up the most interesting and useful clinical cases based on your specialty. To sign up for this email in any of its 10 specialty-specific editions, download the Figure 1 app and update your email preferences.